Table of contents

KNOWLEDGE GIVES CERTAINTY

LAVA PURE in medical application

Because science "creates knowledge"

With LAVA PURE, an effective, safe, and low-side-effect application of zeolite is possible. Its detoxifying and regulating properties can promote health in many ways. Preclinical and clinical studies with the proprietary active ingredient have demonstrated this for over 20 years. 

Overview of Scientific Studies

In the following study overview, you will find a selection of the most important topics that have been scientifically investigated in depth with the premium active ingredient in LAVA PURE. This summary includes only studies that meet scientific standards and withstand objective and factual verification.

 
Studies with the Proprietary Active Ingredient

Please note that the results presented here refer exclusively to the premium active ingredient in LAVA PURE. Since the patented micronization and activation (PMA-Zeolith®) of the high-purity lava stone leads to a modification of its physical effects, the proven effects cannot naturally be transferred to other zeolite products.

DEMONSTRATION OF THE MAIN MECHANISM OF ACTION

Strengthening of the Intestinal Wall Barrier

Main Effect of the Medical Product LAVA PURE Demonstrated by Gold Standard Study

Every medical product requires indisputable proof of its primary physical effect, and in the case of LAVA PURE, it is the strengthening of the intestinal wall barrier through the specific binding of defined toxins in the gastrointestinal tract. 

Leaky Gut – What is a Pathologically Permeable Gut?

Leaky Gut, also known as a permeable or "leaky" gut, is a health disorder in which the intestinal lining becomes too permeable. Normally, only nutrients and necessary substances are allowed into the bloodstream, while harmful substances remain in the intestines and are excreted through the stool. However, in Leaky Gut Syndrome, this filter is damaged, for example, by excessive use of medications like antibiotics, chronic stress, or environmental toxins. This leads to an uncontrolled influx of various irritants into the bloodstream, resulting in symptoms such as bloating, diarrhea, constipation, food intolerances, or abdominal pain. Additionally, systemic issues such as fatigue, headaches, skin irritations, or joint pain can occur. In the long term, Leaky Gut Syndrome can even lead to autoimmune diseases such as rheumatoid arthritis or multiple sclerosis. Our modern lifestyle significantly contributes to the increase of Leaky Gut Syndrome. 

LAVA PURE Regenerates the Intestinal Wall Barrier and Enhances Performance

In the treatment group, there was a significant decrease in zonulin levels, a marker for Leaky Gut, accompanied by an anti-inflammatory tendency. This means that the intake of PMA-Zeolite® leads to faster regeneration of the stress-induced disruption of the intestinal barrier function, and the anti-inflammatory effect relieves the immune system. As a result, endurance athletes experienced an average performance increase of 11%. The reduction of toxic load by LAVA PURE thus alleviates the intestinal lining, promoting normal gut function with positive effects on performance and recovery.


Method – 2014 Study

Clinical gold-standard study (double-blind, randomized, and placebo-controlled) at the Institute for Nutrient Research and Sports Nutrition Green Beat and the Medical University, both in Graz (Austria) / 52 healthy endurance-trained men and women (both physically and mentally stressed people develop Leaky Gut Syndrome, making athletes ideal subjects for this study) / 12-week supplementation with approx. 2 g of PMA-Zeolite® or microcrystalline cellulose (placebo) / stool and blood analyses at the start and after 12 weeks, with a focus on measuring the regulatory protein zonulin as a marker for Leaky Gut.


https://pubmed.ncbi.nlm.nih.gov/26500463/

STRONG BONES

Study on improving bone health

Significant increase in bone density

Osteoporosis is a progressive bone disease, where gradual demineralization leads to reduced bone stability, resulting in significant reductions in quality of life and often treatment-resistant pain. Lifestyle, as well as gradual exposure to environmental pollutants, play a role in the development of osteoporosis.

New Opportunities with the Natural Mineral Zeolite

Medical osteoporosis therapy, including classic osteoporosis medications, have limited success rates. Long-standing experience with the natural mineral zeolite-clinoptilolite and this current osteoporosis study show that regular intake of LAVA PURE can be considered an excellent prevention and treatment option for existing osteoporosis.

5-Year Study Proves

A comprehensive five-year study examined the effects of PMA-Zeolite® on osteoporosis patients. The results showed a significant improvement in bone density and bone formation markers. Patients also reported reduced pain intensity, a lower risk of falls, and improved quality of life. The daily intake of PMA-Zeolite® in LAVA PURE not only prevented the progression of osteoporosis but also improved bone structure.

Method – 2022 Study

5-year human study at the Universities of Rijeka and Pula and the Polyclinic Center in Zagreb (all Croatia) / results were published in June 2022 in a renowned medical journal / 100 osteoporotic patients aged between 56 and 74 years were studied over 5 years for the effects of PMA-Zeolite® on bone structure and quality of life / intake of 3 grams of the active substance 3 times daily / in the first year, the study was randomized, double-blind, and placebo-controlled, after which all participants were switched from placebo to the active substance for ethical reasons / 81 participants completed the first-year evaluation, and 55 participants completed the 5-year evaluation / overall, the active substance in LAVA PURE was well tolerated.

https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.870962/full

POWERFUL GUT FEELING

Treatment of irritable bowel syndrome

The number of days with stomach pain or bloating decreases.

Irritable Bowel Syndrome (IBS) is a functional bowel disorder that is often difficult to diagnose and can remain undetected for a long time. It is typically diagnosed after ruling out other conditions and is often associated with psychosomatic elements and subclinical inflammation, which may be attributed to food intolerances. Particularly, patients with diarrhea-predominant IBS often exhibit increased intestinal permeability (Leaky Gut).

An Overview of Two Scientific Studies

In recent years, two interesting studies have been conducted, suggesting further research on the use of PMA-Zeolite® in irritable bowel syndrome.

LAVA PURE can significantly improve the quality of life in irritable bowel syndrome 

The results of these two studies show significant improvements in seven out of eight quality-of-life criteria from a standardized questionnaire, including a noticeable reduction in abdominal pain and bloating. Patients with diarrhea-predominant IBS particularly benefited from the treatment. 
An interesting detail from the study measuring IBS-related lab values: Both the active substance group and the placebo group showed significant improvement. This indicates a substantial placebo effect and highlights the strong connection between the gut-brain axis and the psyche. However, only in the active substance group were inflammation-specific parameters significantly reduced, accompanied by a supportive increase in anti-inflammatory gut flora.  

Thus, both studies demonstrate that the intake of PMA-Zeolite® can effectively improve the quality of life for IBS patients and significantly reduce specific inflammatory markers in the gut.

Method – 2021 Study

3-month prospective, controlled, double-blind, randomized pilot study at the University of Vienna (Austria) / 41 diagnosed IBS patients / either 3 g of PMA-Zeolite® orally twice daily or microcrystalline cellulose (placebo) / symptom burden, blood and stool inflammation parameters, and changes in the gut microbiome were assessed at the start and after three months.

https://www.nel.edu/pma-zeolite-can-modulate-inflammation-associated-markers-in-irritable-bowel-disease-an-explorative-randomized-double-blinded-controlled-pilot-trial-2781 

Method – 2022 Study 

Nationwide non-interventional study (NIS) on the effectiveness and tolerability of PMA-Zeolite® in Austria in 204 patients with irritable bowel syndrome (IBS) / daily intake of 3 g of PMA-Zeolite® orally twice daily or microcrystalline cellulose (placebo) over a period of 8 weeks / patients documented their symptoms and quality of life (abdominal pain, bloating, number of bowel movements, stool consistency) via a web-based questionnaire and an intake diary.

https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-2223-3963

previous topic

The special quality

next topic

What is LAVA PURE